Klaus Hommels has invested in some of Europe’s most successful start-ups. That includes Spotify, the music-streaming service, and Klarna, a Swedish online payments company valued at more than $2 billion. He has also backed several American tech giants like Facebook and Airbnb, the vacation-rental site.

Now, the German venture capitalist is doubling-down on Europe’s tech sector.

On Monday, Mr. Hommels’s venture capital firm, Lakestar, will announce a new fund worth 350 million euros, or $398 million, one of the largest European fund-raisings so far this year. It is more than double his previous fund, raised in 2013, whose portfolio of start-ups includes Harry’s, the American online shaving company, and Algomi, a London-based social network for bond trading.

Mr. Hommels, 48, who lives in Zurich, plans to spend most of the new money on European start-ups, but also a few American fledging tech companies looking to fast-track their global ambitions. He said that as more industries like automotive and energy embrace new tech trends, he would look at early-stage companies transforming the way people — and traditional companies — lead their daily lives.

“Technology has become integral to how we live,” said Mr. Hommels, who also invested in King Digital, the maker of Candy Crush, but sold his stake before the company went public, missing out on roughly $1 billion. “We won’t be afraid to back start-ups with high valuations if we can accelerate their growth.”

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In part, that is because of companies like King Digital; Mojang, the Swedish gaming company behind Minecraft that Microsoft bought for $2.5 billion; and Zalando, the German e-commerce giant. They have become successful Internet businesses, offering sizable returns to early investors.